We are thrilled to announce that our team has been awarded a research grant by the Swiss National Science Foundation (SNSF) to support our latest project investigating the role of specific immune cells in Glioblastoma.
This project, led by Deniz Kaymak, explores a new and exciting area of cancer research: the role of the immune system at the borders of the brain – specifically in the dura mater (the tough outer layer covering the brain) and the bone marrow in the skull. Recent discoveries show that these areas are not just passive barriers, but active immune hubs that communicate with the brain and may influence how brain tumors grow and evade treatment.
Our research aims to:
Map the immune cells at the brain’s borders and understand how they change when a glioblastoma is present.
Investigate how immune cells from the skull bone marrow contribute to brain tumor progression – and whether they can be redirected to fight the tumor.
Identify potential new treatment strategies that make use of this brain–immune system connection.
By better understanding these “border immune cells,” we hope to find new ways to boost the body’s natural defenses against glioblastoma and open up new options for treatment.
This funding is a major step forward for our lab and allows us to push the boundaries of current brain cancer research, with the ultimate goal of bringing hope to patients and families affected by this devastating disease.