Nazanin Tatari (PhD)
Postdoctoral fellow (2021-Present)

Projects:
1. Preclinical and clinical development of CAR-T cell based therapies for GBM patients
2. GBM personalized and precision medicine

Philip Schmassmann (MD)
MD-PhD student (2019-present)

Projects:
1. Studying GBM tumor microenvironment response to innate immune stimulatory therapies including genetic in-vivo models and pharmacological agents.
2. Understanding the cellular composition of human GBM in a spatial manner using high depth RNA sequencing analysis with the goal of identifying novel immunotherapeutic targets.

 

 

 Sabrina Hogan (PhD)
Postdoctoral fellow/bioinformatician
(2021-Present)

 

 

 

Tomás Martins (M.Sc)
PhD Candidate (2018-Present)

Projects:
1. Combination of CAR T cell therapy and paracrine GAM modulation in GBM using fourth generation CAR T cells and CD47-based innate immune checkpoint blockade
2. Screening and identification of GBM-targeting MR1-restricted T cell clones (in collaboration with De Libero Lab)

 

Manina Etter (MD)
Neurosurgery resident – PhD Student
(2019-present)

Projects:
1. Understanding GBM tumor immune microenvironment and therapy resistance mechanism using CODEX and multiplex cytokine analysis
2. Systematic assessment of SARS-CoV-2 neurotropic capacity in critically ill and COVID-19 patients
3. Clinical assessment of CAR-T cell based therapies for GBM patients
4. Establishing new fluid and image-based biomarkers to investigate the survival and treatment response in GBM patients

 

 

 

 

Deniz Kaymak (MD)
MD-PhD student (2021-present)

Projects:
1. Investigating the role of Inhibitor of DNA-binding 1 (ID1) in tumor-associated microglia and its potential implication in local immunosuppression in glioblastoma.
2. Establishing patient-derived Glioblastoma Organoids and its application as a cancer model.

 

 

Marie-Françoise Ritz (PhD)
Senior Scientist (2018-present)

Projects:
1. Testing new therapies in different glioblastoma mouse models
2. Uncovering the mechanisms of therapy resistance in recurrent glioblastoma.

 

 

 

 

 

Jean-Louis Boulay (PhD)
Scientist and lecturer in experimental and clinical oncology at the University Hospital of Basel/University of Basel.

Projects:
1. Proteomic and genomic data mining of glioma for identifying novel diagnostic and therapeutic biomarkers.
2. Teaching activities at University of Basel include molecular genetics of glioma and advanced French language in medicine and health.

 

Alexandra Gerber (M.Sc.)
Laboratory technician

Project: Assisting the lab with genomic techniques, cell culture and in vitro assays.

 

 

 

 

 

Marta McDaid  (M.Sc.)
Laboratory technician

Project: Assisting the lab with genotyping and histology

 

 Timo Schenker (MD)
Neurosurgery resident
(2023-present)

Project: Generation and preclinical testing of CAR macrophages as a novel immunotherapeutic approach for glioblastoma patients.

Hayget Mohamed (M.Sc)
Intern
(2022-present)

Projects:
Assisting the lab with testing the efficacy of drugs on glioblastoma tumor tissues using 3D bioreactor system, histology, microscopy and in vitro immunoassays.  

 

 

 

 

 

Alumni

  • Anna Wachnowicz
    Lab technician (2018-2020)
  • Gian Marco Vita
    Intern (2018)
  • Valentina Bicvic
    Master student (2020-2021)
  • Tala Shekarian (2018-2022)
  • Carl Zinner
    Postdoctoral fellow (2020-2021)
  • Hanane Baidarjad
    Master student (2019)
  • Celia Durano
    Master student (2021-2022)
  • Cristobal Tostado
    Lab technician (2018-2020)
  • Michèle Amer Salem
    MD student (2019-2020)