


Research Group Leader
(2018-present)
A leader in neuro-oncology with over 35 years of experience, he has advanced the molecular understanding and treatment of brain tumors. He identified key genetic markers in diffuse gliomas and is developing a novel CAR-T cell immunotherapy now entering clinical trials. His clinical innovations include function-preserving surgery for vestibular schwannomas, improved microsurgical techniques for pituitary adenomas, and a new endoscopic approach for tumors invading the cavernous sinus. His work has transformed brain tumor management and surgical practice.

Neurosurgery resident – PhD Student
(2019-present)
Projects:
1. Compartment-resolved plasma and CSF biomarkers integrated with advanced MRI for early differentiation of true progression and pseudoprogression in high-grade gliomas.
2. Using anti-EGFRvIII-SGRP CAR T cells for the locoregional treatment of recurrent glioblastoma: a phase I clinical trial.

MD-PhD student
(2021-present)
Projects:
1. Investigating the role of Inhibitor of DNA-binding 1 (ID1) in tumor-associated microglia and its potential implication in local immunosuppression in glioblastoma.
2. Establishing patient-derived Glioblastoma Organoids and its application as a cancer model.

Postdoctoral fellow
(2023-present)
Projects:
1. Phagocytic synapse enhancers for cancer immunotherapy.
2. Selective Reprogramming of the Tumor Microenvironment via Targeted Delivery of a CSF1-R Inhibitor (more)